Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4520)
Related Products (4520)
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Phenylglyoxylic acid sodium
0 ImagesCat. No.: HY-W010255ACAS No.: 43165-51-1Synonyms: Benzoylformic acid sodiumPhenylglyoxylic acid sodium (Benzoylformic acid sodium) is a metabolite of ethylbenzene and styrene (EB/S) and can be used as a biomarker of exposure to EB/S in human. Phenylglyoxylic acid sodium can be used as drug intermediate for synthesis of antineoplastic compounds.
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Previtamin D3
0 ImagesPrevitamin D3 is an orally active, thermolabile steroidal compound that generates vitamin D3, as well as biologically inactive lumisterol and tachysterol. Previtamin D3 is synthesized in the skin of humans and rats via the UV-B-mediated photoconversion of 7-dehydrocholesterol. Previtamin D3 lacks direct anti-rachitic activity, and its in vivo activity relies on the vitamin D3 it produces. Previtamin D3 can be used in studies related to rickets and vitamin D metabolism.
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ACV Tripeptide TFA
0 ImagesCat. No.: HY-P3519AACV Tripeptide TFA, a tripeptide, is the first dedicated intermediate in the biosynthetic pathway leading to the penicillin and cephalosporin classes of β-lactam natural products in bacteria and fungi. ACV Tripeptide TFA is is synthesized nonribosomally by the ACV synthetase (ACVS) enzyme, which is encoded by the 11 kb The pchAB gene encodes this enzyme. ACV Tripeptide TFA can be used for the biosynthesis of β-lactam antibiotics.
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Boc-Pyr-Oet
0 ImagesSynonyms: (S)-Ethyl-N-Boc-pyroglutamateBoc-Pyr-Oet ((S)-Ethyl-N-Boc-pyroglutamate) is a derivative of L-Pyroglutamic acid (HY-76082). Boc-Pyr-Oet can be used for the synthesis of agents or other compounds.
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13:0 Lyso PE
0 ImagesSynonyms: LGPE 13:013:0 Lyso PE is an intermediate. 13:0 Lyso PE can be used to synthesize tumor-triggered, targeted ammonium bicarbonate liposomes.
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LNA-A(Bz) amidite
0 ImagesCat. No.: HY-W570887CAS No.: 206055-79-0LNA-A (Bz) amidite is a phosphoramidite monomer applicable for oligonucleotide synthesis, such as the synthesis of miniature LNA anti-miRNA-122 antisense oligonucleotides.
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4-Acetamidophenyl acetate
0 Images4-Acetamidophenyl acetate is an impurity of Acetaminophen (HY-66005). 4-Acetamidophenyl acetate acts as an intermediate in the synthesis of Acetaminophen. Acetaminophen is a selective COX-2 inhibitor (IC50=25.8 μM), and is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
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(E)-2-Methyl-2-pentenoic acid
0 Images(E)-2-Methyl-2-pentenoic acid is the component can be used to synthesize the cytotoxic natural product Lactimidomycin.
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Tetrahydrothiophen-3-one
0 ImagesTetrahydrothiophen-3-one is an endogenous metabolite. Tetrahydrothiophen-3-one is a pharmaceutical intermediate that can be used to synthesize thiazole compounds. Tetrahydrothiophen-3-one exists in natural food and has good safety.
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N-Formylmethamphetamine
0 ImagesCat. No.: HY-119326CAS No.: 42932-20-7N-Formylmethamphetamine is an impurity in the synthesis of methamphetamine. N-Formylmethamphetamine is also a by-product of the Nagai reaction.
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L-Threitol
0 ImagesSynonyms: L-1,2,3,4-ButanetetrolL-Threitol (L-1,2,3,4-Butanetetrol) is a four-carbon sugar alcohol. L-Threitol serves as an important pharmaceutical intermediate and can be used in the synthesis of other active compounds, such as anticancer agents and chiral compounds.
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L-Ribulose (solution)
0 ImagesL-Ribulose solution is a 1 M solution of L-Ribulose (HY-121305A) in water. L-Ribulose is an L-form pentulose. L-Ribulose serves as a key precursor for the synthesis of L-ribose and L-nucleoside analogs.
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eIF4A-IN-1 intermediate
0 ImagesCat. No.: HY-176844CAS No.: 3083978-00-8eIF4A-IN-1 intermediate (Compound 71E) is an intermediate of Eukaryotic translation initiation factor 4A (eIF4A) inhibitor. eIF4A-IN-1 intermediate can be used as a cytotoxic payload for synthesis of antibody-drug conjugates (ADCs).
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8-Hydroxyquinoline-2-carbaldehyde
0 Images8-Hydroxyquinoline-2-carbaldehyde is a quinoline derivative with the functions of DNA intercalation, hydroxyl radical scavenging and superoxide radical scavenging. 8-Hydroxyquinoline-2-carbaldehyde serves as a precursor for synthesizing Schiff base ligands with DNA intercalation activity and antioxidant properties. 8-Hydroxyquinoline-2-carbaldehyde can be used in relevant research across multiple fields including materials science and biomedicine.
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6-Hydroxynicotinic acid (Standard)
0 Images6-Hydroxynicotinic acid (Standard) is the analytical standard of 6-Hydroxynicotinic acid (HY-W001996). This product is intended for research and analytical applications. 6-Hydroxynicotinic acid is an intermediate in the oxidation of Nicotinic acid (HY-B0143) by Pseudomonas fluorescens and metabolite. 6-Hydroxynicotinic acid can be isolated from root exudates of Cucumis melo. 6-Hydroxynicotinic acid disrupts the Auxin signaling pathway. 6-Hydroxynicotinic acid inhibits haustoria precursor formation in Phlipanche aegyptiaca.
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2-Aminoindan-2-carboxylic acid
0 ImagesCat. No.: HY-W241255CAS No.: 27473-62-72-Aminoindan-2-carboxylic acid is a conformationally restricted Phenylalanine analog and molecular building block. 2-Aminoindan-2-carboxylic acid constitutes a component of allosteric LFA-1 antagonists targeting the LFA-1/ICAM-1 interaction. 2-Aminoindan-2-carboxylic acid serves as a molecular building block for various biologically active peptides, including μ-receptor-selective opioid analogs, activated protein C inhibitors, and histone deacetylase inhibitors. 2-Aminoindan-2-carboxylic acid can be used in the research of autoimmune diseases, inflammatory diseases, opioid receptor-related diseases, antidiuresis-related diseases, and cancers.
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2-Benzylaniline
0 ImagesCat. No.: HY-W016323CAS No.: 28059-64-5Synonyms: 2-Aminodiphenylmethane2-Benzylaniline is an intermediate. 2-Benzylaniline can be used to synthesize Compound 15. Compound 15 shows an affinity for the D3 receptor with a Ki of 4654 nM. 2-Benzylaniline can be used in research on mental illnesses.
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Isonicotinic acid-d4
0 ImagesIsonicotinic acid-d4 is the deuterium labeled Isonicotinic acid (HY-I0736). Isonicotinic acid is a pyridine carboxylic acid compound and also a metabolite of Isoniazid (HY-B0329). Derivatives of Isonicotinic acid exhibit antiviral activity against influenza viruses.
